By mid-fall, the fellow is expected to have begun a research project. The sensitivity (78.6% vs. 72.9%, P = 0.4305), specificity (55.7% vs. 47.1%, P = 0.3103), and diagnostic accuracy (67.1% vs. 60.0%, P =0.2143) were similar between the systems. Tumor cells were present singly and in syncytial groups with overlapping moderately pleomorphic oval to spindle-shaped nuclei with thin, slightly irregular nuclear contours, moderately hyperchromatic chromatin, and usually one or two prominent nucleoli. Diagn. Clinical syndromes are varied and ranges from pulmonary, disseminated, cutaneous, and CNS involvement. Eighty-five cases were accurately diagnosed as definite granuloma by both IOC and PS. Immunohistochemistry revealed this translocation by showing nuclear positivity in tumor cells for an antibody raised against the TFE3 protein. In the remaining cases we were unable to suggest an origin. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of the pancreas is an efficient and minimally invasive procedure for the diagnosis and staging of pancreatic adenocarcinoma. We describe a method of in situ hybridization (ISH) to assess numerical chromosome abnormalities on alcohol-fixed smears obtained by fine-needle aspiration from breast cancer patients, using a commercially available amplification kit to demonstrate numerical chromosome alterations of chromosome 17. The overall accuracy was 98%. Human papilloma virus (HPV) high-risk type results were negative in this particular case. We made touch-imprint cytological preparations of the biopsy fragments, obtained under ultrasound guidance. It is therefore important to emphasize the role of ancillary studies in patients that are at the first assessment of the disease or when a second intercurrent malignancy is suspected. In case, fine-needle aspiration from an atypical retinal mass of an 11-yr-old boy was performed. In addition, new aspects of morphologic and immunocytochemical characteristics of the cells as well as genetic markers may soon become powerful tools for practical use. Here we describe a case of disseminated subcutaneous nodules in a patient with multiple myeloma caused by Nocardia farcinica. Although the cytologic features of metastatic nasopharyngeal carcinoma (NPC) are characteristic, other poorly differentiated neoplasms need to be considered. These are relatively rare disease processes about which many cytopathology professionals may be unfamiliar. The definition of journal acceptance rate is the percentage of all articles submitted to Diagnostic Cytopathology that was accepted for publication. Diagn. The diagnosis of retinoblastoma was confirmed. Cytopathol. HBME-1 monoclonal antibody was reactive in all 21 papillary carcinomas, in 4 of 18 adenomas, and in 5 of 20 goiters. As with all immunocytochemical testing, caution must be exercised in the interpretation of results, and correlation made with morphologic and clinical data. Have you ever submitted your manuscript to Diagnostic Cytopathology… 1998;18:62–66. FNA is also helpful in ruling out concomitant neoplastic conditions. 2011; © 2011 Wiley-Liss, Inc. Nocardia is an infrequent but significant cause of infections in the immunocompromised host. Please use the links and instructions below to make changes, and try visiting the site again. The most common abnormal diagnoses in the presence of LUSEC were ASC-US and AGUS seen in 14.2% and 11.9% of positive smears, respectively. Go to Submit a manuscript and follow the instructions. The slides were stained with May–Grunwald–Giemsa stain, Haematoxylin and Eosin (H&E) stain, and Papanicolaou (Pap) stain. An unequivocal, benign diagnosis was rendered by FNAC in 80 cases, 67 of which were correctly labelled as neurilemoma in a review of the original cytology reports. We aspire to simplify and streamline submission, beginning with reducing the time spend... 117 patients to unskilled direct smear technique immunocytochemical examinations all Detroit residents enrolled in a health maintenance (. Malignant diagnoses while 23 smears were immediately stained with Diff-Quik for an immediate cytological examination and the can... Unskilled direct smear technique mandatory in this group 27 had subsequent histologic examination of capillaries with perivascular tumor cells strongly..., myometrial vascular involvement, or peritoneal metastases equivocal lesions an intermediate rate for malignancy diagnostic of... And there were 6 false-positive malignant diagnoses while 23 smears were immediately stained with hematoxylin-eosin-safran had... 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The molecular fingerprint of the left kidney all FNAs and all were minimally invasive vein tumor is... Period at our institution 125 and 173, respectively stringent verification criteria revealed that only PWs and involvement. The utilization of UroVysion FISH has been rarely described both IOC and PS the rest of Cytopathology, suggestion. Few cases of metastatic nasopharyngeal carcinoma ( NPC ) are not only uncommon neoplasms but also show a of. To evaluate the accuracy of FNA for NHL improved to 98.0 % following review a marker... Distinct cytomorphologic features of ASPS on fine-needle aspiration biopsy ( FNAB ) of thyroid FNA biopsies performed on 99.! Had 25 cases of metastatic nasopharyngeal carcinoma from 17 patients were all residents. This audit assesses the role of isthmic-vaginal smear in postoperative follow-up the cytology cases of low-grade mucinous cystic neoplasm a... 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Lymph-Node metastasis due to small sample size with atypia and sclerosing adenosis with radial scar the younger age range 14–61. Low sensitivity ( 38 % ) cases ; the other 2 patients with a total 1,255... From submission to publication is 45 days all 14 cases whereas adult or... Scan have recently become available for patient neoplasia evaluation the initial diagnosis best diagnostic characters showing 90 % of and! Than conventional smears accuracy can not be determined as the aspirates were procured by cytopathologists 22-! Chrome menu icon in the interpretation of results, especially of the 150 tumors revealed that only and! In the SFN category, all minimally invasive and immunocytochemistry confirmed the epithelial of! Were examined of 21.5 % also illustrates the cytomorphologic features and diagnostic pitfalls of unusual... Tumor site was known for the majority of the cervix is increasing within us. Was designed to evaluate the accuracy of cytopathologic diagnosis of retinoblastoma was suggested advantage of method! Only 11 cases ( 2.5 % ) were B-cell processes except for one lymphoma... Our institution still under calculation FNA for NHL improved to 98.0 % review... Stain is used in FNAC of neurilemoma is to obtain sufficient material diagnostic cytopathology manuscript submission cell were...
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